Hi, I've tried installing the devel version of affy (1.3.23) for R 1.8.0 in Windows 2000, and got an error after typing > library(affy) Error in open.connection(con, "rb") : unable to open connection In addition: Warning message: cannot open compressed file `C:/rw1080/library/affy/R/all.rda' Error in library(affy) : .First.lib failed But when I built the Win32 package from source, it worked fine. The Windows build I made is at : http://bioinf.wehi.edu.au/limmaGUI/affy_1.3.23.zip You can install.packages("affy",contriburl="http://bioinf.wehi.edu.au/limmaGUI ") temporarily! Regards, James ---------------------------------------------------------------------- ---- James Wettenhall Tel: (+61 3) 9345 2629 Division of Genetics and Bioinformatics Fax: (+61 3) 9347 0852 The Walter & Eliza Hall Institute E-mail: wettenhall@wehi.edu.au of Medical Research, Mobile: (+61 / 0 ) 438 527 921 1G Royal Parade, Parkville, Vic 3050, Australia http://www.wehi.edu.au