Affy SNP array analysis
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@james-w-macdonald-5106
Last seen 10 hours ago
United States
Hi all, As you may or may not know, Affy now has an array for SNP mapping. Are there plans to make a package for analyzing this sort of data, or is this too far afield from gene expression to fall under the Bioconductor umbrella? TIA, Jim James W. MacDonald Affymetrix and cDNA Microarray Core University of Michigan Cancer Center 1500 E. Medical Center Drive 7410 CCGC Ann Arbor MI 48109 734-647-5623
SNP Microarray Cancer affy SNP Microarray Cancer affy • 1.6k views
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@vincent-j-carey-jr-4
Last seen 8 weeks ago
United States
> > As you may or may not know, Affy now has an array for SNP mapping. Are > there plans to make a package for analyzing this sort of data, or is > this too far afield from gene expression to fall under the Bioconductor > umbrella? I would say this is less a question of falling under an umbrella (Bioconductor is directed at general computational biology) and more a question of resources. We have a lot of work to do to stabilize and deploy the next release. I have yet to see data from these SNP chips; if there are any public resources that will help us to consider class design and basic strategies, please let us know. The genotyping chips are probably a good opportunity for someone looking to make an impact on the project.
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@holger-schwender-344
Last seen 10.2 years ago
I think this is a very interesting idea, and I might probably contribute to such a package since I'm currently working on a project that is concerned with SNP data (mainly cluster and classification analysis, no SNP detection). But I'm only interested in co-authoring such a package. So if anyone else is interested in making a package for SNP analysis, please send me an email. I have already written some function, but I've just started. Greetings Holger > > > > As you may or may not know, Affy now has an array for SNP mapping. Are > > there plans to make a package for analyzing this sort of data, or is > > this too far afield from gene expression to fall under the Bioconductor > > umbrella? > > I would say this is less a question of falling under an umbrella > (Bioconductor is directed at general computational biology) and more > a question of resources. We have a lot of work to do to stabilize > and deploy the next release. > > I have yet to see data from these SNP chips; > if there are any public resources that will help us to consider > class design and basic strategies, please let us know. The > genotyping chips are probably a good opportunity for someone > looking to make an impact on the project. > > _______________________________________________ > Bioconductor mailing list > Bioconductor@stat.math.ethz.ch > https://www.stat.math.ethz.ch/mailman/listinfo/bioconductor > -- COMPUTERBILD 15/03: Premium-e-mail-Dienste im Test\ --------...{{dropped}}
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@holger-schwender-344
Last seen 10.2 years ago
I think this is a very interesting idea, and I might probably contribute to such a package since I'm currently working on a project that is concerned with SNP data (mainly cluster and classification analysis, no SNP detection). But I'm only interested in co-authoring such a package. So if anyone else is interested in making a package for SNP analysis, please send me an email. I have already written some function, but I've just started. Greetings Holger > > > > As you may or may not know, Affy now has an array for SNP mapping. Are > > there plans to make a package for analyzing this sort of data, or is > > this too far afield from gene expression to fall under the Bioconductor > > umbrella? > > I would say this is less a question of falling under an umbrella > (Bioconductor is directed at general computational biology) and more > a question of resources. We have a lot of work to do to stabilize > and deploy the next release. > > I have yet to see data from these SNP chips; > if there are any public resources that will help us to consider > class design and basic strategies, please let us know. The > genotyping chips are probably a good opportunity for someone > looking to make an impact on the project. > > _______________________________________________ > Bioconductor mailing list > Bioconductor@stat.math.ethz.ch > https://www.stat.math.ethz.ch/mailman/listinfo/bioconductor > -- COMPUTERBILD 15/03: Premium-e-mail-Dienste im Test\ --------...{{dropped}}
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Greetings, We ran some 10K SNP Chips last week during training at the Boston University Microarray Core Facility (http://www.bu.edu/genome/microarray/index.htm). They seem like a very good product and Affymetrix will be coming out with a 100K SNP chip next year. Pretty cool. On the downside (though it will give us something to do) the algorithms for determining SNP calls are just as screwy as the algorithms from the expression chips. Good luck. Garrett Frampton -----Original Message----- From: bioconductor-bounces@stat.math.ethz.ch [mailto:bioconductor-bounces@stat.math.ethz.ch] On Behalf Of Holger Schwender Sent: Thursday, September 11, 2003 6:55 PM To: bioconductor@stat.math.ethz.ch Cc: bioconductor@stat.math.ethz.ch Subject: Re: [BioC] Affy SNP array analysis I think this is a very interesting idea, and I might probably contribute to such a package since I'm currently working on a project that is concerned with SNP data (mainly cluster and classification analysis, no SNP detection). But I'm only interested in co-authoring such a package. So if anyone else is interested in making a package for SNP analysis, please send me an email. I have already written some function, but I've just started. Greetings Holger > > > > As you may or may not know, Affy now has an array for SNP mapping. Are > > there plans to make a package for analyzing this sort of data, or is > > this too far afield from gene expression to fall under the Bioconductor > > umbrella? > > I would say this is less a question of falling under an umbrella > (Bioconductor is directed at general computational biology) and more > a question of resources. We have a lot of work to do to stabilize > and deploy the next release. > > I have yet to see data from these SNP chips; > if there are any public resources that will help us to consider > class design and basic strategies, please let us know. The > genotyping chips are probably a good opportunity for someone > looking to make an impact on the project. > > _______________________________________________ > Bioconductor mailing list > Bioconductor@stat.math.ethz.ch > https://www.stat.math.ethz.ch/mailman/listinfo/bioconductor > -- COMPUTERBILD 15/03: Premium-e-mail-Dienste im Test\ --------...{{dropped}} _______________________________________________ Bioconductor mailing list Bioconductor@stat.math.ethz.ch https://www.stat.math.ethz.ch/mailman/listinfo/bioconductor
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