I am using coefficient of variation as a way of filtering affymetrix data and I am new to using this method for filtering data: I have a query based on the genefilter package. Does this command: x <-filterfun(cv(0.5)) mean removing genes that have a coefficient of variation of more that 50 %? thanks [[alternative HTML version deleted]]

Hi Manisha, From the help page: Description: 'cv' returns a function with values for 'a' and 'b' bound. This function takes a single argument. It computes the coefficient of variation for the input vector and returns 'TRUE' if the coefficient of variation is between 'a' and 'b'. Otherwise it returns 'FALSE' Usage: cv(a=1, b=Inf, na.rm=TRUE) Arguments: a: The lower bound for the cv. b: The upper bound for the cv. This seems pretty clear to me - if this is confusing can you tell us what part needs fixing? Best, Jim Manisha Brahmachary wrote: > I am using coefficient of variation as a way of filtering affymetrix data and > I am new to using this method for filtering data: > > > > I have a query based on the genefilter package. > > > > Does this command: > > > > x <-filterfun(cv(0.5)) mean removing genes that have a coefficient of > variation of more that 50 %? > > > > thanks > > > [[alternative HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor -- James W. MacDonald, M.S. Biostatistician Affymetrix and cDNA Microarray Core University of Michigan Cancer Center 1500 E. Medical Center Drive 7410 CCGC Ann Arbor MI 48109 734-647-5623