Hi, I am trying to estimate the variability technical replicates from different microarray platforms. The few papers I found on this topic and current opinion seems to suggest that technical replicates are not required for microarrays. However, I like to estimate the distribution of variablity of the genes and confirm this myself. Can someone kindly point me to some studies with technical replicates that makes their data publicly available? Many thanks in advance. Regards, Adai

Have you checked the MAQC project? A link for the datasets used in this project is given on the main web site. A series of papers describing the different studies and datasets are publicly available from Nature Biotechnology (see link on the main MAQC page): http://www.fda.gov/nctr/science/centers/toxicoinformatics/maqc/index.h tm Good luck! -Christos Christos Hatzis, Ph.D. Nuvera Biosciences, Inc. 400 West Cummings Park Suite 5350 Woburn, MA 01801 Tel: 781-938-3830 www.nuverabio.com > -----Original Message----- > From: bioconductor-bounces at stat.math.ethz.ch > [mailto:bioconductor-bounces at stat.math.ethz.ch] On Behalf Of > Adaikalavan Ramasamy > Sent: Tuesday, April 15, 2008 8:13 AM > To: bioconductor at stat.math.ethz.ch > Subject: [BioC] published studies with technical replicates > > Hi, > > I am trying to estimate the variability technical replicates > from different microarray platforms. The few papers I found > on this topic and current opinion seems to suggest that > technical replicates are not required for microarrays. > > However, I like to estimate the distribution of variablity of > the genes and confirm this myself. Can someone kindly point > me to some studies with technical replicates that makes their > data publicly available? > > Many thanks in advance. > > Regards, Adai > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor > >