Hi, With R 2.6.2 on Ubuntu Gutsy affyio install (via biocLite.R) fails. apt-get install zlib1g-dev seems to fix it, but this isn't immediately obvious from the error message: ...load of fread_functions errors... make: *** [fread_functions.o] Error 1 chmod: cannot access `/usr/local/lib/R/library/affyio/libs/*': No such file or directory Sorry if you already know about this. Just thought it might save someone else ten mins of faffing about. Cheers, Cass xx