Hi all, The adoption of proteomics approaches (based on two dimensional gels or others means) into biological research is increasing and give important data sets. Distilling biological signifiance from these data sets remain a challenge (a challenge shared by gene expression analysis). So, I would like to know if some people has already worked on the analysis of such data. As in gene expression analysis, an important problem could be the normalisation data in the case of the comparison of different biological conditions. Does somebody have experience in these questions? Regards, Olivier. -- ------------------------------------------------------------- Martin Olivier INRA - Unit? prot?omique LIRMM - IFA/MAB 2, Place Viala 161, rue Ada F-34060 Montpellier C?dex 1 34392 Montpellier C?dex 5 Tel : 04 99 61 26 02 Tel : O4 67 41 86 71 martinol@ensam.inra.fr