Try limma or maanova. --Naomi At 11:44 AM 1/22/2008, greg lefebvre wrote: >Hi all, >I have received time series dataset which I could not control the >experimental design. > >And here it is. This is a 2 conditions time series (placebo/treatment) with >5 time points. >The main issue I encounter is that the number of replicates at each time >point is not the same: >time ttt placebo >t0 2 7 >t3 3 6 >t7 3 6 >t14 2 5 >t28 5 4 > >I tried to use the timecourse package but obviously I can't set the required >replicate matrix. >Unless I remove some samples (more or less justified by their poor quality) >so that the number of sample becomes constant, does anyone could give me >some good advice ? > >In advance many thanks > >Greg > > [[alternative HTML version deleted]] > >_______________________________________________ >Bioconductor mailing list >Bioconductor at stat.math.ethz.ch >https://stat.ethz.ch/mailman/listinfo/bioconductor >Search the archives: >http://news.gmane.org/gmane.science.biology.informatics.conductor Naomi S. Altman 814-865-3791 (voice) Associate Professor Dept. of Statistics 814-863-7114 (fax) Penn State University 814-865-1348 (Statistics) University Park, PA 16802-2111