Mark, We are also shipping samples to process using the Illumina Methylation beadarray and I was under the impression that the facility would be able to provide the raw bead level data as well as the summaries. Based on your response, perhaps I need to clarify this with them. Can you provide the explicit instructions for modifying the settings.xml file prior to scanning so that bead level data is available? Thanks! Best, Kellie Kellie J. Archer, Ph.D. Assistant Professor Department of Biostatistics & Massey Cancer Center Virginia Commonwealth University 730 East Broad St., 3-022 Richmond, VA 23298-0032 phone: (804) 827-2039 fax: (804) 828-8900 e-mail: [1]kjarcher at vcu.edu website: [2]www.people.vcu.edu/~kjarcher References 1. mailto:kjarcher at vcu.edu 2. http://www.people.vcu.edu/%7Ekjarcher