Dear Bioc, I want to use the Knn function, from packages(class), to classify sample from a cDNA dataset in which there are some missing values. When I run the script, the function complains about missing values, so I checked for some strategies to overcome the problem. One way could be to fit the missing values on the data itself, with pamr.knnimpute, but I don't like the idea, as I maight overfit the data itself. On the other side I was looking for a strategy to make knn accept missing values but I could not find. do you have any suggestion? -- Claudio ------------------------------------------------------ Leggi GRATIS le tue mail con il telefonino i-mode? di Wind http://i-mode.wind.it/