Dear list, I would like to analyse circadian rhythms in gene expression. I found some references regarding a methodology called "single cosinor method" with which such an analysis should be possible. Does anyone have experience with this kind of analysis, especially with the cosinor method? Can anyone point me to references? Is there a R or Bioconductor package to help in this kind of analysis? I hope, this is not too much off topic, Thanks Lewin Dr. med. L. Eisele Klinik f?r H?matologie Universit?tsklinik Essen Hufelandstr. 55 45122 Essen

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