I don't know where to start: I'm planning on generating a single feature polymorphism (SFP) map for 11 primate strains of malaria using a high density array. Some previous work on these primate malarias found a significant negative correlation between a quantitative measure of virulence and the number of host species each primate malaria could infect using a least squares model. I want to somehow test or establish an association with the SFP divergence score for genes implicated in host specificity to this other data- the host number-virulence correlation. I don't know what would be the best statistical approach- some likelihood method, a multivariate correlation? Sincerely, Betty