Hi,
that is more a question of interest:
Affymetrix provides the probe interrogation positions and they can be
found in the corresponding "probe" package of each chip. But is this
in
respect to the currently used methods and aside from
displaying/matching
the probes at the correct chromosomal location only for the sake of
completeness? Or is there in fact some analysis method (background
correction, normalization, investigation etc.) which makes use of this
information?
regards,
Benjamin
--
Benjamin Otto
Universitaetsklinikum Eppendorf Hamburg
Institut fuer Klinische Chemie
Martinistrasse 52
20246 Hamburg
Hi Benjamin,
botto wrote:
> Hi,
>
> that is more a question of interest:
>
> Affymetrix provides the probe interrogation positions and they can
be
> found in the corresponding "probe" package of each chip. But is this
in
> respect to the currently used methods and aside from
displaying/matching
> the probes at the correct chromosomal location only for the sake of
> completeness? Or is there in fact some analysis method (background
> correction, normalization, investigation etc.) which makes use of
this
> information?
I don't know of any method that uses the chromosomal position in
computing expression values.
Best,
Jim
>
> regards,
>
> Benjamin
>
>
--
James W. MacDonald, M.S.
Biostatistician
Affymetrix and cDNA Microarray Core
University of Michigan Cancer Center
1500 E. Medical Center Drive
7410 CCGC
Ann Arbor MI 48109
734-647-5623
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