Mohammad - A possible start is to acquire the excellent Springer book (2005) entitled "Bioinformatics and Computational Biology Solutions Using R and Bioconductor" with editors Gentlemen, Carey, Huber, Irizarry, and Dudoit. Chapter 2, 'Preprocessing High-density Oligonucleotide Arrays' addresses many aspects of this question that may interest you. Regards, Greg W. Gregory Alvord, Ph.D. Director, Statistical Consulting Services Computer and Statistical Services National Cancer Institute at Frederick Post Office Box B Frederick, MD 21702-1201 Phone: 301.846.5101 Facsimile: 301.846.6196 E-Mail gwa at css.ncifcrf.gov -----Original Message----- From: bioconductor-bounces@stat.math.ethz.ch [mailto:bioconductor- bounces@stat.math.ethz.ch] On Behalf Of Mohammad Esad-Djou Sent: Tuesday, November 21, 2006 9:55 AM To: bioconductor at stat.math.ethz.ch Subject: [BioC] tasks of Background Correction and PM Correction in Preprocessing methods Hello All, I would like to separate tasks of Background Correction and PM Correction in Preprocessing methods. Unfortunately I do not find a uniform definition in literature. Sometimes are tasks of PM Correction and Background Correction similarly, e.g. Correction of Cross hybridisation. Where and how can I clear (and correct!) Definition about it find? Thanks, Mohammad Interdisciplinary Centre for Bioinformatics University of Leipzig H?rtelstr. 16 - 18 D-04107 Leipzig _______________________________________________ Bioconductor mailing list Bioconductor at stat.math.ethz.ch https://stat.ethz.ch/mailman/listinfo/bioconductor Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor