p-values
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@richard-hartley-301
Last seen 10.2 years ago
Sir/Ms Is there a function within a bioconductor library that allows for the generation of p-values or statistical significances? Thanks R Hartley [[alternate HTML version deleted]]
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rgentleman ★ 5.5k
@rgentleman-7725
Last seen 9.6 years ago
United States
Hi, I think you need to be a bit more specific (and please do not repost the same message). What hypothesis are you interested in? A p-value is basically a piece of information that is relevant to a specific hypothesis, since there are rather a large number of such hypotheses and you have not said what you want it is a bit difficult to answer you. There are many, many different options for generating tests of hypotheses and for doing lots of other things too. Robert On Wed, May 21, 2003 at 12:06:51PM +0100, Richard Hartley wrote: > Sir/Ms > Is there a function within a bioconductor library that allows for the > generation of p-values or statistical significances? > Thanks > R Hartley > > [[alternate HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor@stat.math.ethz.ch > https://www.stat.math.ethz.ch/mailman/listinfo/bioconductor -- +--------------------------------------------------------------------- ------+ | Robert Gentleman phone : (617) 632-5250 | | Associate Professor fax: (617) 632-2444 | | Department of Biostatistics office: M1B20 | | Harvard School of Public Health email: rgentlem@jimmy.harvard.edu | +--------------------------------------------------------------------- ------+
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I don't know if this is the best place to post this question but I will try anyway. I have two experiements for which I use one-way matched-randomized ANOVA for the analysis and I would like to compare different treatments in the two experiments. The only common group in the two experiments are the controls. Is there any ANOVA design that allows me to make this comparison taking into consideration the confounding effect? Any help would be greatly appreciated. Isaac A representation of the experiments follows: Experiment 1 Control1 Treat1 Treat2 Blk1 s1 s2 s3 Blk2 s4 s5 s6 Blk3 s7 s8 s9 Experiment 2 Control2 Treat3 Treat4 Blk1 s1a s2a s3a Blk2 s4a s5a s6a Blk3 s7a s8a s9a Control1 and Control2 I are the same control cell line. I would like to compare Treat1 to Treat3 and Treat 4 and also I would like to compare Treat2 to Treat3 and Treat4. The fact that those experiments are done in two different blocks will confound the interpretation. Can I use the common control group to build a model? Should I include one of the treatments in future experiments to test my model?
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@alessandrosemeriacramontit-256
Last seen 10.2 years ago
Any statistical test return a p-value, for example look at the R-library "ctest" (Classical Tests) for the most common ones. Good job A.S. ---------------------------- Alessandro Semeria Models and Simulations Laboratory The Environment Research Center - Montecatini (Edison Group), Via Ciro Menotti 48, 48023 Marina di Ravenna (RA), Italy Tel. +39 544 536811 Fax. +39 544 538663 E-mail: asemeria@cramont.it

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