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odlc@uchicago.edu
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@odlcuchicagoedu-1782
Last seen 10.3 years ago
Hello,
I am trying to understand how normalize.AffyBatch.quantiles
works. From what I understand of the code, it seems that
rows (corresponding to a probe) which contain even a single
NA are dropped; then, the quantile-normalization method
described in Botstein et al. is applied to the remaining rows,
and these normalized rows are put back into the original
batch.
In other words, values in a row that contains NA's
remain unchanged.
Questions:
- Is this really how it works?
- If yes, is this the intended behavior?
Thank you,
Omar.