I am getting the following error: > peter48.raw <- ReadAffy(widget=TRUE) Error in structure(.External("dotTcl", ..., PACKAGE = "tcltk"), class = "tclObj") : [tcl] ambiguous option "-col": must be -column, -columnspan, -in, -ipadx, -ipady, -padx, -pady, -row, -rowspan, or -sticky. The first thing that happens when I execute the ReadAffy command is the "File Browser" comes up and I select the CEL files. When I select the "Finish" button, I get the error message and a thin "Sapmle Information" window pops up (the word Sample is misspelled). I just downloaded R 1.7.0 and getBioC(libName="all",release="devel") which all loaded just fine. I have windows 2000. My startup commands to R are: "C:\Program Files\R\rw1070\bin\Rgui.exe" --max-mem-size=4000M library(affy) Sys.putenv("TCL_LIBRARY"="c:/Program Files/Tcl/lib/tcl8.3") Any help or suggestions would be most appreciated. Thanks much, Dick ********************************************************************** ********* Richard P. Beyer, Ph.D. University of Washington Tel.:(206) 616 7378 Env. & Occ. Health Sci. , Box 354695 Fax: (206) 685 4696 4225 Roosevelt Way NE, # 100 Seattle, WA 98105-6099