I'm trying to install the depmap package on an R 3.6.3 system. When I do it through Bioconductor, I get: package ‘depmap’ is not available (for R version 3.6.3). So I tried installing from source and I get this error: error: ‘rnai_19Q2’ not found in ExperimentHub.

Here is the full output from the installation attempt:

> sudo R --vanilla  CMD INSTALL depmap_1.3.1.tar.gz
* installing to library ‘/usr/local/lib/R/site-library’
* installing *source* package ‘depmap’ ...
** using staged installation
** R
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
Using temporary cache /tmp/RtmpgYP52U/BiocFileCache
Warning: `select_()` is deprecated as of dplyr 0.7.0.
Please use `select()` instead.
This warning is displayed once every 8 hours.
Call `lifecycle::last_warnings()` to see where this warning was generated.
Warning: `filter_()` is deprecated as of dplyr 0.7.0.
Please use `filter()` instead.
See vignette('programming') for more help
This warning is displayed once every 8 hours.
Call `lifecycle::last_warnings()` to see where this warning was generated.
snapshotDate(): 2019-04-29
Using temporary cache /tmp/RtmpgYP52U/BiocFileCache
Using temporary cache /tmp/RtmpgYP52U/BiocFileCache
Using temporary cache /tmp/RtmpgYP52U/BiocFileCache
snapshotDate(): 2019-04-29
Using temporary cache /tmp/RtmpgYP52U/BiocFileCache
Using temporary cache /tmp/RtmpgYP52U/BiocFileCache
Error: package or namespace load failed for ‘depmap’:
 .onLoad failed in loadNamespace() for 'depmap', details:
  call: FUN(X[[i]], ...)
  error: ‘rnai_19Q2’ not found in ExperimentHub
Error: loading failed
Execution halted
ERROR: loading failed
* removing ‘/usr/local/lib/R/site-library/depmap’

So do I need to take the plunge and upgrade to R 4.0 to get depmap to install?

When BiocManager::install("depmap") reports that the package is not available for your version of R, it's telling the truth. Trying to work around this results in an error. Apparently, it relies on resources present in ExperimentHub that were added when the package was added to Bioconductor.

If you'd like to use depmap, then I suggest updating your R to the current version (4.0.2).