Hi, I am trying to use your Bioconductor affy package. I am following the Howto load Affymetrix data. I have entered in the following: library (affy) ##load the affy package and I'm getting the following error: Error in getClass(Class) : "MIAME" is not a defined class In addition: Warning messages: 1: There is no package called 'Biobase' in: library(package, character.only = TRUE, logical = TRUE, warn.conflicts = warn.conflicts, 2: There is no package called 'Biobase' in: library(package, character.only = TRUE, logical = TRUE, warn.conflicts = warn.conflicts, Error in library(affy) : .First.lib failed Can you tell me what I am doing wrong? Thank you in advance. Kim Vaughan Research Associate Medical College of Wisconsin [[alternate HTML version deleted]]

> I am trying to use your Bioconductor affy package. I am following the > Howto load Affymetrix data. I have entered in the following: Via what mechanism did you acquire the affy package? > 1: There is no package called 'Biobase' in: library(package, > Can you tell me what I am doing wrong? Thank you in advance. As per the affy DESCRIPTION file, affy depends on package Biobase. There are various methods of acquiring the Biobase package: - If you have R-1.7.0 for Windows you can select the "Install Packages from Bioconductor" option under "Packages" pulldown. - You can download directly from our website: http://www.bioconductor.org/repository/release1.1/package/html/Biobase .html or http://www.bioconductor.org/repository/devel/package/html/Biobase.html Depending on if you want the release1.1 or devel versions, respectively. - You can use getBioC() (and if you had already used getBioC, I'm not sure why you don't have Biobase): http://www.bioconductor.org/reposToolsDesc.html -Jeff