Ensembl v75 annotation - difference between non-coding and intron

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sara.blocquiaux • 0

@sarablocquiaux-21717

Last seen 4.9 years ago

Hi all,

I annotated my methylation data (Illumina 850K beadchip) according to Ensembl version 75. The following gene sections are linked to the probes:

Promoter
5'UTR
CDS
Intron
3'UTR
Non-coding
Intergenic

I was wandering...Non-coding regions are within introns or intergenic regions. Why is this a different category then? What does "non-coding" represent?

Thanks in advance!

Sara

annotation • 486 views

ADD COMMENT • link 4.9 years ago sara.blocquiaux • 0

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You need to be more explicit. The only 850k beadchip I know of is the Cyto-SNP 850, which isn't a methylation array. Perhaps you mean the EPIC? Also, what do you mean by 'I annotated my methylation data'? How? Using what package? Is this even a Bioconductor question?

Do note that Non-coding is not likely to refer to DNA, but instead to a type of RNA that doesn't get translated to protein, which would more accurately be described as Untranslated. But it is relatively common to call things like miRNA, snoRNA, lncRNA, etc 'Non-coding'.

ADD REPLY • link 4.9 years ago James W. MacDonald 67k

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