DESeq2 standard error estimate (lfcSE)
1
0
Entering edit mode
shintzen • 0
@shintzen-18932
Last seen 6.0 years ago

I have quite a few results of DESeq2 where the lfcSE is very near to 1. I don't fully understand how I should interpret this value, and though I have read through the first several pages of google with a few different search terms, I am still not confident that I fully understand.

From what I've understood you can convert these to fold change errors using this formula: 2^(coef - SE) and 2^(coef + SE) and if you multiple lfcSE by normal quantiles (e.g. qnorm(.025)), you can construct confidence intervals for the coefficients but I still don't know how to apply that information to my experiment. Should I disregard anything where the lfcSE is near 1?

I am happy to be pointed to some good descriptions of this value, outside of the R Documentation.

deseq2 • 1.7k views
ADD COMMENT
0
Entering edit mode
@mikelove
Last seen 2 days ago
United States

Can you show some examples of this lfcSE near 1?

ADD COMMENT

Login before adding your answer.

Traffic: 569 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6