Hi all,

I am facing an error using on the package “VariantAnnotation”

It is one of the dependencies for my package hosted on GitHub and currently a lot of the users with latest R version are facing this error.

‘invalid class "VRanges" object: 'strand' should be a 'factor' Rle with levels c("+", "-", "*")’

The package works fine with the R version 3.3.2 but fails with the above mentioned error on the higher or latest R version.

Could you point out to what is different and why am I facing this error that is R version dependent?

Looking forward to your help.

Thanks

Each version of Bioconductor is designed to work with an associated set of packages. For example the current release version of Bioconductor is 3.7 and the devel version is 3.8 (both use R 3.5). You can see the package versions associated with each on the build reports:

https://www.bioconductor.org/checkResults/release/bioc-LATEST/

https://www.bioconductor.org/checkResults/devel/bioc-LATEST/

My guess is that you have a mixture of old and new packages in your installation. Please show the output of sessionInfo() and check your installation with BiocInstaller::biocValid().

Valerie