Is C adjusted for purity?
1
0
Entering edit mode
twtoal ▴ 10
@twtoal-15473
Last seen 1 day ago
United States

Several PureCN output files have "C" columns containing estimated copy number.  Is the data in these columns adjusted for purity?  That is, do they reflect the copy number of the tumor tissue and not the normal tissue that is mixed in with it?  If not, am I correct to think that the adjustment would be:

Adjusted_C = (Unadjusted_C - 2*(1-purity)) / purity

 

PureCN Adjusted C • 1.0k views
ADD COMMENT
0
Entering edit mode
@markusriester-9875
Last seen 2.0 years ago
United States

Yes, these are already  adjusted. No need for manual calculations. 

ADD COMMENT

Login before adding your answer.

Traffic: 917 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6