I looked to see if this question was asked, but did not see anything, so if this is a duplication, I  apologize.

I am trying to add DEseq packages to R 3.4.3 in windows10, which runs as R console.

> source("http://www.bioconductor.org/biocLite.R")
Bioconductor version 3.6 (BiocInstaller 1.28.0), ?biocLite for help
> biocLite("DESeq")
BioC_mirror: https://bioconductor.org
Using Bioconductor 3.6 (BiocInstaller 1.28.0), R 3.4.3 (2017-11-30).
Installing package(s) ‘DESeq’
trying URL 'https://bioconductor.org/packages/3.6/bioc/bin/windows/contrib/3.4/DESeq_1.30.0.zip'
Content type 'application/zip' length 2896350 bytes (2.8 MB)
downloaded 2.8 MB

package ‘DESeq’ successfully unpacked and MD5 sums checked

then I use the tab "packages.> load packages " DEseq

Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: ‘BiocGenerics’

(many objects are masked from several packages)

Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.

Loading required package: locfit
locfit 1.5-9.1   2013-03-22
Loading required package: lattice
    Welcome to 'DESeq'.

instructions for DEseq then say : library("DEseq")

but I get error: there is no package called DEseq, so I tried the next step which is  a function called estimateSizeFactors, but I get "unable to find an inherited method for the function", but DEseq is in use?

since I am new to R, I am completely confused.

Do you want to install DESeq2?

Try the instructions here:

https://bioconductor.org/packages/release/bioc/html/DESeq2.html