CAMERA fold changes per gene set?
0
0
Entering edit mode
chris86 ▴ 420
@chris86-8408
Last seen 4.9 years ago
UCL, United Kingdom

Dear bioconductor/ limma developers

I was wondering if there is a straightforward way of getting fold changes per gene set out when I run CAMERA or any of the gene set functions in limma. This is because I need to plot them. I am enjoying using the general pipeline, but at the moment to get the fold changes I am having to code it out manually.

Currently I am getting the log(TPMs) for every gene in the pathway, calculating the mean, then calculating a second mean per group. Next I divide one group value by the other.

Is this even the best way to approximate the fold change per pathway between groups?

Best wishes,

Chris

limma • 664 views
ADD COMMENT

Login before adding your answer.

Traffic: 801 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6