Hello all, We are having a problem analyzing a large data set (30 Affy soybean arrays, ~61K probesets). I moved from my PC to our server running IRIX, but I'm still getting the same error message of "unable to allocate vector size...". There are 12 G of physical memory on the server plus another 17 G swap; the R process doesn't even touch a fraction of this, so it's not a memory limitation problem. I found a similar discussion of this on the listserve back in January 2005, but the only fix suggested was to make sure R > 2.0 and BioC >1.5. Our versions are beyond this, so does anyone have any other ideas? Thanks, Jenny Session output: > norm <- normalize(rawdata) Error: cannot allocate vector of size 317553 Kb ^D > sessionInfo() R version 2.1.1, 2005-06-20, mips-sgi-irix6.5 attached base packages: [1] "tools" "methods" "stats" "graphics" "grDevices" "utils" [7] "datasets" "base" other attached packages: soybeancdf affy reposTools Biobase "1.5.1" "1.6.7" "1.5.19" "1.5.12" Jenny Drnevich, Ph.D. Functional Genomics Bioinformatics Specialist Roy J. Carver Biotechnology Center University of Illinois, Urbana-Champaign 330 ERML 1201 W. Gregory Dr. Urbana, IL 61801 ph: 217-244-7355 fax: 217-265-5066 e-mail: drnevich at uiuc.edu